Malaria Molecular Epidemiology: Lessons from the International Centers of Excellence for Malaria Research Network.

Am J Trop Med Hyg
Authors
Keywords
Abstract

Molecular epidemiology leverages genetic information to study the risk factors that affect the frequency and distribution of malaria cases. This article describes molecular epidemiologic investigations currently being carried out by the International Centers of Excellence for Malaria Research (ICEMR) network in a variety of malaria-endemic settings. First, we discuss various novel approaches to understand malaria incidence and gametocytemia, focusing on Plasmodium falciparum and Plasmodium vivax. Second, we describe and compare different parasite genotyping methods commonly used in malaria epidemiology and population genetics. Finally, we discuss potential applications of molecular epidemiological tools and methods toward malaria control and elimination efforts.

Year of Publication
2015
Journal
Am J Trop Med Hyg
Volume
93
Issue
3 Suppl
Pages
79-86
Date Published
2015 Sep
ISSN
1476-1645
URL
DOI
10.4269/ajtmh.15-0005
PubMed ID
26259945
PubMed Central ID
PMC4574277
Links
Grant list
U19 AI089676 / AI / NIAID NIH HHS / United States
U19 AI089674 / AI / NIAID NIH HHS / United States
U19 AI089696 / AI / NIAID NIH HHS / United States
U19 AI089686 / AI / NIAID NIH HHS / United States
U19 AI089672 / AI / NIAID NIH HHS / United States
U19 AI089702 / AI / NIAID NIH HHS / United States