Cooperation for Better Inhibiting.

Chem Biol
Authors
Keywords
Abstract

Cladosporin is an antimalarial drug that acts as an ATP-mimetic to selectively inhibit Plasmodium lysyl-tRNA synthetase. Using multiple crystal structures, Fang et al. (2015) reveal in this issue of Chemistry & Biology the fascinating mechanism responsible for cladosporin selectivity.

Year of Publication
2015
Journal
Chem Biol
Volume
22
Issue
6
Pages
685-6
Date Published
2015 Jun 18
ISSN
1879-1301
URL
DOI
10.1016/j.chembiol.2015.06.002
PubMed ID
26091164
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